Sandra M. Garraway, PhD

Assistant Professor

Emory University School of Medicine

Office: Department of Physiology

Phone: (404)-727-7417: Lab (404)-727-0344

Fax: (404)-727-2648

Email: sgarraw@emory.edu

Additional Contact Information

Mailing Address:

Emory University School of Medicine

Whitehead Research Building, room #605G
615 Michael Street

Atlanta, GA 30322

Additional Websites

Biography

Education:

PhD, University of Manitoba

Postdoctoral Fellow, SUNY Stony Brook

Postdoctoral Fellow & Instructor in Pharmacology, Weill Cornell Medical College

Research Assistant Professor, Texas A&M University

Assistant Professor, Emory University School of Medicine, 2013-present

Research Area: Nociceptive plasticity and the development of pain after Spinal Cord Injury

Research

Noxious information resulting from injury to the periphery is processed in the spinal cord dorsal horn before it is transmitted to the brain. Damage to the spinal cord produces several devastating, often life threatening effects. About 70% of spinal cord injury patients experience pain, many of which experience chronic neuropathic pain. Despite the prevalence of neuropathic pain after spinal cord injury, the neural mechanisms underlying its development are poorly understood. In addition, there are no clear factors that predict if and when neuropathic pain develops.

Our research focuses on identifying adaptive versus maladaptive cellular plasticity that influences functional recovery and the development of pain after spinal cord injury. Using rodent models of SCI (contusion and transection) our research combines behavioral, molecular and electrophysiological techniques to investigate:

   I.         Development of segmental and below-level pain after SCI

   II.         Interactions between autonomic dysfunction and neuropathic pain

   III.         Neuronal/glial mechanisms influencing spinal nociceptive plasticity

   IV.         Biological and/or experiential factors that predict the development of pain after SCI

   V.         Primary afferent plasticity that contributes to pain after SCI

The role BDNF-TrkB signaling plays in afferent plasticity and pain after SCI

Publications