Emory Home Search the Emory Web

Leona G. Young

Professor Emeritus of Physiology

Ph.D., Emory University, 1967, J.D., Georgia State University, 1988

Research Interests:

The long-term goal of our research is to increase understanding of the molecular mechanisms involved in the epididymal maturation of primate sperm and how perturbations of this maturation might be used for manipulating reproductive capacity. Our focus is on the EP2 protein that is specific to the epididymis and that is dependent on androgens for its synthesis and secretion. We are using molecular biological methodologies to study both the epididymal specificity and the androgen dependence of EP2. We are using immunological methodologies to study the physiological function of the EP2 protein. Because epididymal proteins can affect sperm maturation, interference with the synthesis and secretion of EP2 could have profound effects on sperm fertilizing capacity. Therefore, these studies can have a significant impact on future strategies for the development of technologies for enhancing and for inhibiting fertilization.

Publications:  PubMed search

Department of Physiology
Emory University School of Medicine
615 Michael Street, Suite 648
Atlanta, GA 30322-3110

Email Address:  leona.young@emory.edu