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Douglas C. Eaton

Distinguished Professor and Chair of Physiology

Ph.D., University of California, San Diego, 1971

Member of Graduate Program:  Biochemistry, Cell, and Developmental Biology

Director:   Center for Cell and Molecular Signaling

Research Interests:

The goal of my research is to examine the cellular signaling mechanisms which regulate membrane ion transport and cellular homeostasis. To examine these signaling mechanisms, I use contemporary methods of cellular and molecular biology including patch voltage clamp methods and expression of cloned signaling molecules in heterologous expression systems. There are three main areas of cellular signaling research in my laboratory. First, I have been particularly interested in the cellular responses which involve steroid hormones and other lipid molecules particularly how some of these molecules are responsible for regulation of total body sodium balance. This work has lead us recently to examine defects in cellular signaling which may be responsible for some types of hypertension and electrolyte disorders. Second, I have been examining the signaling mechanisms responsible for the responses of renal cells to growth factors and vasoactive substances like Angiotensin II. This work has direct relevance to understanding the renal pathology of diabetes. Finally, I am interested in the signaling mechanisms which control fluid balance in the lungs. This work may provide an understanding of the pathophysiological mechanisms responsible for lung edema and acute lung injury.

Publications:  PubMed search

Department of Physiology
Emory University School of Medicine
615 Michael Street, Suite 648
Atlanta, GA 30322-3110
Office: 404--727-7421

Email Address:  douglas.eaton@emory.edu