Jason Miranda, Ph.D.

Senior Scientist
Pfizer Corporation
Cambridge, United Kingdom


Education

B.S., Life Science, Arizona State University, Glendale, AZ, 2001
Ph.D., Neuroscience, University of Texas at Austin, 2007
FIRST Postdoctoral Fellow, Department of Biology, Emory College, 2007-2009


Research Statement

Auditory evoked behavior, such as a mother mouse retrieving a pup that has wandered from the nest or a female approaching a male to mate, requires that the animal be in a particular behavioral or physiological state and that the stimulus occurs in a particular context. This phenomenon is found across vertebrate taxa and suggests that auditory processing that leads to natural behavior is a dynamic process. My specific interests lie in how neural plasticity, arising from changes in reproductive state or social environment, influences the encoding, decoding and perception of natural auditory stimuli. I will address these questions in the auditory cortex of a mouse model for maternal behavior where auditory communication largely occurs through ultrasonic vocalizations.

 

Publications

Miranda, J.A. & Liu, R.C.  (2009)  Dissecting natural sensory plasticity: hormones and experience in a maternal context. Hearing Research, 252(1-2):21-8.

Miranda, J.A. & Wilczynski, W. ( 2009) Sex differences and androgen influences on midbrain auditory thresholds in the green treefrog, Hyla cinerea. Hearing Research DOI: 10.1016/j.heares.2009.04.004.

Miranda, J.A. & Wilczynski, W. (2009) Female reproductive state influences the auditory midbrain response. Journal of Comparative Physiology, A. 195(4), 341-349.

Miranda, J.A., Oliveira, R.F., Carneiro, L.A., Santos, R.S., Grober, M.S. (2003) Neurochemical correlates of male polymorphism and alternative reproductive tactics in the Azorean rock-pool blenny, Parablennius parvicornis. Gen Comp Endocrinol., 132(2):183-9.

Oliveira, R.F., Carvalho, N., Miranda, J., Gonçalves, E.J., Grober, M., Santos, R.S. (2002) The relationship between the presence of satellite males and nest-holders' mating success in the Azorean rock-pool blenny, Parablennius sanguinolentus parvicornis. Ethology, 108:223-235.

Kishida, M., Mclellan, M., Miranda, J.A., Callard, G.V. (2001) Estrogen and xenoestrogens upregulate the brain aromatase isoform (P450aromB) and perturb markers of early development in zebrafish (Danio rerio). Comparative Biochemistry and Physiology Part B: Boichemistry and Molecular Biology, 129:261-268.

Oliveira, R.F., Miranda, J.A., Carvalho, N., Gonçalves, E.J., Grober, M.S., Santos, R.S. (2000) Male mating success in the Azorean rock-pool blenny, Parablennius sanguinolentus parvicornis: the effects of body size, male behavior and nest characteristics. Journal of Fish Biology, 57:1416-1428.

 

Pfizer Corporation
Cambridge, United Kingdom
Email: miranda.jason.a@gmail.com


Emory University School of Medicine
Department of Physiology
Atlanta, GA 30322-3110
(404) 727-7410 Office ~ (404) 727-2648 FAX

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